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Pharma & Life Sciences Clinical Trial Overrun

How a pharma company prevented a €5M clinical trial delay.

CRA resource conflicts were invisible in spreadsheets. Praeveo detected the pattern 6 weeks before escalation.

€5M
delay prevented
6 weeks
earlier detection
3
CRA conflicts resolved

A Phase III clinical trial with 12 sites across Europe was progressing on paper. But the lead CRA was allocated to 3 parallel trials, enrollment pace at 2 sites had dropped 34% below plan, and a document review backlog was growing silently.

Traditional reporting showed “on track” — the underlying data showed an impending 3-month delay. The cost of that delay: €5M in extended site operations, patient retention, and regulatory re-scheduling.

No single system connected the dots between CRA allocation, enrollment pace, and document backlogs. Until Praeveo did.

Three signals. One impending delay.

Critical

Lead CRA capacity conflict across 3 trials

Resource allocation data showed the lead CRA assigned to 3 concurrent trials with overlapping site visit windows in weeks 14–18.

High

Site 7 enrollment pace −34% vs plan

Two sites showed sustained enrollment decline over 4 consecutive weeks. Pattern consistent with pre-delay trajectory in historical trials.

Watch

Document review backlog growing — 12 pending reviews

Regulatory document queue increasing week over week. At current pace, review completion would miss the submission window by 3 weeks.

From invisible risk to timely intervention.

€5M
delay cost prevented
6 weeks
earlier risk detection
Resolved
CRA reassigned before capacity crisis
On time
trial completed within 2 weeks of original timeline
“The signals were all there — in our data. We just couldn’t see them. Praeveo connected the dots we were missing.”
— VP Clinical Operations, Global Pharma Company

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